A common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins provides insights into potential new targets for antimicrobial development.
February 25, 2026
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Each half of the board hinges in two places for minutely customizable center tenting. It has low profile keys with responsive yet quiet mechanical switches. It works wirelessly or corded, has thumb cluster keys and, of course, it’s all fully programmable. It's lovely to type on and the thumb clusters and modules make it easy to keep your fingers in the home position to minimize repetitive travel.
homebrew-core has one Ruby file per package formula, and every brew update used to clone or fetch the whole repository until it got large enough that GitHub explicitly asked them to stop. Homebrew 4.0 switched to downloading a JSON file over HTTP, because users wanted the current state of a package rather than its commit history. But updating a formula still means opening a pull request against homebrew-core, because git is where the collaboration tooling lives. Instead of using git as a database, what if you used a database as a git?